Acetylcholinesterase inhibition starting from extracts of Bauhinia variegata L., Bauhinia var. candida (Aiton) Buch.-Ham., and Bauhinia ungulata L.

نویسندگان

  • Kamilla Monteiro dos Santos
  • Priscila Sant'Ana Gonçalves
  • Maria José Nunes de Paiva
  • Guilherme Araújo Lacerda
چکیده

INTRODUCTION A treatment to the Alzheimer's disease consists inhibition of the acetylcholinesterase, which is responsible for the acetylcholine control in the synapses. METHODS We have investigated the potential of inhibition of the acetylcholinesterase produced by hexane extracts of leaves, branches, and flowers from three Bauhinia specimens, which is based on the technique of thin layer chromatography and on identifying the organ of the plant that possesses larger concentration of inhibitors. RESULTS Retention factor analysis shows values of 0.31aA, 0.31aA, and 0.46aB for flowers B. variegata, B. var. candida, and B. ungulata, respectively. CONCLUSIONS The flower extract of B. ungulata is the most suitable for further studies on this inhibition.

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عنوان ژورنال:
  • Revista da Sociedade Brasileira de Medicina Tropical

دوره 44 6  شماره 

صفحات  -

تاریخ انتشار 2011